SYPHILIS

SYPHILIS

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum.

It is most common in people with a penis and having sex with people with a penis aged between 32 and 44. In Belgium, the number of cases has risen by 24% a year since the 1990s.

It's important to note that syphilis does not confer immunity, which means that an infected and cured person can be reinfected at a later date. Around 25% of cases reported each year are reinfections.

Syphilis is transmitted: 

- sexual contact (vaginal, oral and/or anal) 

- direct contact with lesions (chancres* and red patches) 

- during pregnancy (from mother to child)

Syphilis is more likely to be transmitted by a person with a penis than by a person with a vulva.

Syphilis can also be transmitted through blood transfusions or intravenous drug use. However, transmission by blood transfusion is very rare in Belgium, as donor blood undergoes very strict screening for syphilis.

 

*Isolated ulceration of the skin or mucous membranes constituting the initial stage of several contagious diseases, most often venereal (Larousse, n.d.).

Syphilis has four stages with specific symptoms. These stages do not necessarily follow one another. For example, it's quite possible to develop stage 2 without going through stage 1.


Phase 1 (10 to 90 days after infection)

Syphilis usually begins with the appearance of one or more painless sores on the skin or mucous membranes, on the penis, glans, testicles, clitoris, vagina, anus, nipples, rectum, lips, mouth and throat, and more rarely in other parts of the body. These sores disappear on their own, without treatment, within 3 to 6 weeks.

The carrier remains contagious, however, and if left untreated during the first phase, the infection will progress to a second phase.


Phase 2 (6 weeks to 6 months after the first wound)

- Appearance of skin rashes, often localized on the palms of the hands or soles of the feet;

- Possible joint and muscle pain;

- Flu syndrome with fever, swollen lymph nodes, headache and sore throat;

- Patchy hair loss.

Although these symptoms may disappear naturally without treatment, the infection remains, and in the absence of treatment, the disease progresses to its third phase, known as the "latent" phase.


Phase 3 - Latent phase

No symptoms are present during the latent phase of infection, but there is a risk of developing tertiary syphilis if left untreated. This latent phase can last for several years, during which syphilis remains contagious.


Phase 4 - Tertiary syphilis or neurosyphilis (3 to 30 years or more after infection)

At this stage, the infection is no longer transmissible, but the bacteria remain active, multiplying and spreading throughout the body, causing severe damage to vital organs and the central nervous system (heart, brain, eyes, bones).

During the final phase of a syphilis infection, the emergence of : 

- skin or testicular tumors,

- tumors in other tissues, 

- cardiovascular symptoms such as aortic aneurysm or aortic valve insufficiency,

- degeneration of the central nervous system, with symptoms such as dementia, tremors and loss of productivity.

If left untreated, a third of individuals infected with syphilis develop, sometimes years later, a severe form known as tertiary syphilis, which can lead to serious complications such as cardiac and neurological problems, including stroke, loss of coordination, insensitivity, paralysis, loss of vision and hearing loss. Tertiary syphilis has dramatic health consequences and is associated with a very high mortality rate.

Transmission of syphilis from a pregnant person to their baby can occur during pregnancy.

Pregnant people are generally screened for syphilis, and those who are infected receive antibiotic treatment. Treatment during pregnancy helps prevent transmission of syphilis from the pregnant person to the child.

- Blood sampling ; 

- Smear of lesions when present; 

- Immediate result test/Rapid diagnostic test (TROD)

Treatment of syphilis requires the administration of antibiotics.

To protect yourself from syphilis, you can: use STI protection methods, avoid contact with blood (tattooing - single-use needle and ink pot, piercing - single-use or sterilized needle) and contact with skin rashes. 

Condoms reduce the risk of exposure, but do not offer total protection, as syphilis can be transmitted during sexual touching* and oral sex (practices less often protected).

A person who has sex with a syphilis chancre is at greater risk of contracting HIV or another STI.

 

*mutual masturbation and sexual friction

Regular screening for people with multiple partners: syphilis is easy to treat and of no consequence when diagnosed early.

Other STIs

Other infections